Nicholson never played for the Royals, and had played his last major-league game on October 1, 1967. Because he spent all but 10 games of the 1967 season, and all of 1968 in the minors, he was left out of the 1968 Topps set.
Dave was signed by the Orioles in 1958, and played 2 full seasons in the minors. After 18 games with triple-A Miami in 1960, he made his major-league debut with the Orioles on May 24th. After another full season in the minors in 1961, Dave returned to Baltimore in 1962 as a backup outfielder.
In January 1963, Nicholson was traded to the White Sox (with pitcher Hoyt Wilhelm and infielders Pete Ward and Ron Hansen) for shortstop Luis Aparicio. Dave was the Sox' regular left fielder in 1963, and shared the job with others in 1964. With newly-acquired Danny Cater taking over left field, Dave was relegated to the bench for all of 1965.
Nicholson was traded to the Astros in December 1965 for pitcher Jack Lamabe, and a year later he was shipped to the Braves with pitcher Bob Bruce for 3rd baseman Eddie Mathews and infielder Sandy Alomar.
After spending most of the next 2 seasons with the Braves' AAA team in Richmond, Dave was purchased by the expansion Royals in October 1968. He spent his final professional season (1969) pinch-hitting for the expansion Royals' triple-A team in Omaha, Nebraska.